Comparative study of CNS tuberculoma and Neuro-cysticercosis with CT and MRI

AUTHOR(s) : Das I, Choudhury MK, Choudhury H
DOI No. : 10.31741/ijhrmlp.v8.i1.2022.11



Background and aims: CNS infections are usually diagnosed by clinical assessment and laboratory investigations, particularly cerebrospinal fluid (CSF) analysis, combined with radiologic findings. Radiology plays a vital role by providing the differential diagnosis and occasionally identifying a particular entity with a characteristic appearance. Imaging is also crucial for identifying disease complications and assessing response to treatment. Material and methods: Cases are referred to the Radiology department based on clinical signs and symptoms. Contrast-enhanced Computed Tomography (CT) & Magnetic Resonance Imaging (MRI) of the brain were done routinely. Written consent was taken in all cases for the contrast study. Additional sequences like Magnetic Resonance Spectroscopy (MRS), Diffusion-Weighted Imaging (DWI), and Susceptibility Weighted Imaging (SWI) characteristics of the lesions were evaluated. Results: Our study group comprised 50 cases of CNS infection. Males are more commonly affected than females. Neurocysticercosis (NCC) was the most common (60%), followed by tuberculosis. Headache (90%) and vomiting (80%) were the common presenting symptoms. Tuberculoma lesions mainly were between 1-3 cm in size. 60% of cases showed multiplicity. 78% of the NCC cases showed multiple lesions, with perilesional oedema present in 74% of the cases. Mass effect was not a predominant finding in NCC cases. The T2 intensity of lesion varied between hyperintensity and heterointensity, with most cases (75%) being T2 hyperintensity. Conclusion:  Our study found MRI superior to CT in diagnosing and characterizing tuberculoma and NCC lesions.

Keywords: CNS Infection; Neurocysticercosis; Diffusion-Weighted Imaging; Magnetic Resonance Spectroscopy.

Registered Office Address:
House No: One, Karmabir Bordoloi Path, Wireless,
Rukmini Nagar, Dispur-06, Assam, India

Mobile: 09435017802
IJHRMLP is an open-access journal, and the articles published are instantly available to read and use again. The published articles thus can be downloaded, shared, and reused without restriction if the contributing original authors are appropriately cited. Author(s) retain the copyright of their article, with articles licensed to AHRME and the journal following the Creative Commons Attribution License (CC-BY).
Maintain By Prism Infosys